{"id":108,"date":"2019-12-09T19:20:57","date_gmt":"2019-12-09T18:20:57","guid":{"rendered":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/?p=108"},"modified":"2019-12-10T10:06:29","modified_gmt":"2019-12-10T09:06:29","slug":"fabz-acp-protein-complex-structure-interaction","status":"publish","type":"post","link":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/?p=108","title":{"rendered":"FabZ ACP protein complex structure interaction"},"content":{"rendered":"\n<p>Video animation for Mechanism of Action of FasB-ACP interaction. Commisioned by Liang Zhang for Cell  Research paper publication.  Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China   <\/p>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-embed-youtube wp-block-embed is-type-video is-provider-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"FabZ ACP protein complex structure interaction animation catalytic MOA liang zhang 3Dciencia Hi2\" width=\"580\" height=\"326\" src=\"https:\/\/www.youtube.com\/embed\/r85vZkBemHg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><figcaption> Fatty acid biosynthesis (FAS) is a vital process in cells. Fatty acids  are essential for cell assembly and cellular metabolism. Abnormal FAS  directly correlates with cell growth delay and human diseases, such as  metabolic syndromes and various cancers. The FAS system utilizes an acyl  carrier protein (ACP) as a transporter to stabilize and shuttle the  growing fatty acid chain throughout enzymatic modules for stepwise  catalysis. <\/figcaption><\/figure>\n\n\n\n<p> Based on Paper: Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like  catalytic mechanism of dehydratase in fatty acid biosynthesis. Cell  Research volume 26, pages1330\u20131344(2016).<br> Lin Zhang, Jianfeng Xiao, Jianrong Xu, Tianran Fu, Zhiwei Cao, Liang Zhu, Hong-Zhuan Chen, Xu Shen, <br> Hualiang Jiang &amp; Liang Zhang. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Video animation for Mechanism of Action of FasB-ACP interaction. Commisioned by Liang Zhang for Cell Research paper publication. Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China Based on Paper: Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis. Cell Research [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[19,17,5],"tags":[14,15,13,12,16],"_links":{"self":[{"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=\/wp\/v2\/posts\/108"}],"collection":[{"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=108"}],"version-history":[{"count":2,"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=\/wp\/v2\/posts\/108\/revisions"}],"predecessor-version":[{"id":117,"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=\/wp\/v2\/posts\/108\/revisions\/117"}],"wp:attachment":[{"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=108"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=108"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tresddos.com\/ramonandrade\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=108"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}